“There is nothing like looking, if you want to find something. You certainly usually find something, if you look, but it is not always quite the something you were after.” J.R.R. Tolkien
The long words really get to me sometimes "Bovine dialyzable leukocyte extract"? Is that a nice name for bloody extract of squished cow? There seems to be a possibility of a scam in the supplements labelled 'transfer factors' - some FIP cats are getting http://transferfactor-4-life.com/thesecretoftransferfactors.aspx
I think however there is legitimate research: As Prof Lipkin says - raw meat is full of goodies!
Bovine dialyzable leukocyte extract (bDLE) is a dialyzate of a heterogeneous mixture of low molecular weight substances released from disintegrated leukocytes of the blood or lymphoid tissue obtained from homogenized bovine spleen. bDLE is clinically effective for a broad spectrum of diseases. To determine whether bDLE improves survival and modulates the expression of pro-inflammatory cytokine genes in LPS-induced, murine endotoxic shock, Balb/C mice were treated with bDLE (1 U) after pretreatment with LPS (17 mg/kg). The bDLE improved survival (90%), suppressed IL-10 and IL-6, and decreased IL-1β, TNF-α, and IL-12p40 mRNA expression; and decreased the production of IL-10 (P<0.01), TNF-α (P<0.01), and IL-6 (P<0.01) in LPS-induced, murine endotoxic shock. Our results demonstrate that bDLE leads to improved survival in LPS-induced endotoxic shock in mice, modulating the pro-inflammatory cytokine gene expression, suggesting that bDLE is an effective therapeutic agent for inflammatory illnesses associated with an unbalanced expression of pro-inflammatory cytokine genes such as in endotoxic shock, rheumatic arthritis and other diseases.
Hoping the ever helpful Dr Norris will comment soon. The amazing claims for some supplements are worse than hair product ads. It pays to be skeptical and do your due diligence though the horrible knowledge that FIP is a rapid disease means this is a real dilemma. In hindsight I would like to erase the two week delay popping homeopathic drops on an intermittently febrile cat while I tracked down and checked out feline interferon (FOI). Hence I hope this blog will be helpful to others in some way rather than just more to read and worry over.