This is a story I got from one of the FIP yahoo groups. It has stayed in the drafts folder of this blog for over a year. I didn't
manage to contact Tigger's mum for more details, a picture and so on. Post is copied
verbatim as I expect Tigger's mum wants the story out
there. So sadly I
don't have details of diagnosis, no bloodwork - that's a caveat, it may not be FIP but it's hard to think of what else could have made him so sick for 6 weeks; my notes say wet FIP. I can see the precipitating immune suppressing causes are pretty common ones. The move was big one as I recall; I think Tigger had to take a plane ride and was received at the other end unwell. He is a little older than usual. Most importantly Tigger's
successful treatment has commonalities with other survivors -
antibiotics combined with IV fluids and an immune stimulant - in this
case interferon ( i think probably it is feline interferon since this
cat is in Europe. ) special food (again wish I knew the details!) and intense daily attention.
Hi. I have a rambunctious male 5 year old cat. His name is Tigger. 5 months ago, I moved to Turkey. He had a shot for Luekemia (sp prob wrong) Anyway BAD idea. Don't ever get your cat a shot for this without getting him tested for the corona virus. I'm not sure if I spelled that right either but it's easy enough for you to google.
Anyway, the move and shot sent him into full blown FIP. His eyes were rolling to the back of his head, sky high fever, skin and bones, boy did I thought he was a goner. We started interferon and vitamins, antibiotics and Iv every day for a month and a half. Each day I spent 2-3 hours at the vet. 5 months later, he is alive and fat and happy. Each day I give him 2 vitamins. One in the morning and one at night. And they have garlic in them, yes, garlic.
If you make a serious commitment to keep your cat alive, I believe you have a pretty good shot of beating this with the help of interferon. I also give him food for sensitive systems and NO treats!! TReats do not help any cat. I have a second cat that seems to be fine and probably live to be 20. Tigger is living on borrowed time but I treasure ever extra moment. I also keep their cat box VERY clean. 2ce a day I clean it. My heart goes out to all owners with fip cats. It's heart wrenching, I know.
My other thought, a year of case history reviews later, is that I feel vets are not paying enough attention to fluid and salt (electrolyte) managment in FIP cats. Sick inapetant cats are easily dehydrated as they are desert animals
designed to get most of their fluids from freshly killed prey. Vets seem to devote all the owner's resources to diagnostic gymnastics while their patient slips away from under their noses. Any reasonably sick human wheeled into an ER would be instantly hooked to an IV while this is worked out.
Also on the home front I
doubt this cat was left to waste his remaining energy dragging himself
to a litterbox too far, up a flight of stairs to the bedroom or being needlessly stressed by a bath (this is not sarcasm - I do actually
know of someone who went to the trouble of getting PI then bathed their FIP
cat. Predictably it took a downhill turn from there and is not listed on my
survivors log.)
"drink the wine drink the wine- music, good friends, I'm not dyin' today" ~ Tori Amos
Tomten
has been doing the Lazarus cat dance back from the brink for past eight
months. He was heading downhill in late June and a surgery was
performed hoping the granulomas were from a foreign body like string.
However he crashed after the surgery and was very poorly for several
weeks.
"Tomten continues to fight but is growing
steadily weaker. He has taken to spending the entire day in a pile of
stuffed animals in the kids play room. My husband can get him to eat a
little bit. He is becoming wobbly on his feet. My husband is still
hopeful and when he eats I am too but in my gut I think he is in his
final weeks."
But his vets didn't think he was in
pain, didn't toss in the towel and a week later on July 26th he turned
the corner with last ditch antibiotics, steroids and high energy paste.
Cassie
wrote - "I am scared to to even post this in case it jinxes us but Tom
has had a great two days. Since going on the last ditch antibiotics and
back on pregnazone (sic) and the high calorie paste he is feeling so
much better. He is eating!! He is hanging out with us and Gizmo instead
of hiding in the stuffed animal pile. When he got sick last year we did 3
things. Interferone, prednasone, and a course of antibiotics for the
herpes which was bad. Since surgery Tom was off the pregnazone and he
had antibiotics on the operating table but none since. Keeping my
fingers crossed he is turning a corner but too scared to hope. Is it
possible he has 18 lives?"
I wonder if I've been
underestimating the support antibiotics can provide an ailing cat - even
if it's not the primary illness, knocking down the numbers of bacteria
multiplying out of their normal range due to host debilitation, may
allow the cat enough space to muster his reserves for the fight. "lipo polysaccharides (LPS ) from many bacterial species will initiate acute inflammatory responses in mammals". Maybe we should have tried harder with Mishka's lump.
So
his ultrasounds didn't show any other lumps - he went back to happy and
active. And Cassie was back to square one diagnostically.
"He
continues to do well since the antibiotics and the return to Pred. I
caught him playing kitty smack down with Gizmo last night first time in 3
months. I don't know who was happier Gizmo or me. I think Gizmo was
letting him win since he out weighs Tomten 3 to 1 at this point. Tomten
couldn't have a more loving brother. Now that I have him back again my
thoughts are turning to how do I keep him alive and delay the granulomas
from coming back. I started doing some internet research trying to
figure out what besides FIP causes granulomas and responds so
dramatically to antibiotics and prednisone. I came across Inflammatory
Bowel disease (IBD). The literature says its rare but can cause granulomas."
Some informational links and my thoughts on IBD and inflammation:
http://feline-nutrition.org/health/feline-inflammatory-bowel-disease-nature-and-treatment - My gut feeling (haha a pun) is that Feline Irritable Bowel its not far off human IBD. What you eat determines the gut microbiome. We have a little human friend who had to have a fecal transplant to get rid of his awful colitis. He is a very sick boy who is now off all his meds! Anyone with Crohn's disease or colitis who wants to get cured contact Dr Borody in Sydney.
http://www.2ndchance.info/inflambowelcat.htm Although i dont have direct cat experience with IBD per se I noted our other pets have better skin on a proper raw diet, which I imagine reflects the state of the gut as it is basically the same as skin - both are made of epithelial cells. Mishka was the big diet fail - i always thought she'd come a cropper on dry food diet but figured (wrongly) I had time to transition her to a 'better' diet. Wrong again - commercial petfood is just wrong, I had no idea it was all so dreadful until she got ill. Now i know even the tinned food, though 'complete', is still highly inflammatory.
http://raypeat.com/articles/nutrition/carrageenan.shtml - carageenan is seaweed - not meant to be eaten by cats but it's the thickener in most commercial petfood. It is known to incite inflammation, in fact it's used experimentally to do just that when you need to make a wound to test a cure on! I have no idea why they dont use gelatin instead, which is anti inflammatory and being connective tissue supplies all the right things for building connective tissue for both humans and animals http://raypeat.com/articles/articles/gelatin.shtml
" For everyone of us that succeeds, it's because there's somebody there to show you the way out. " ~ Oprah
Blade lies in Michigan USA with Joni Swanson, still hale and happy in Jan 2013 over two years since first diagnosis. When I stumbled across Blade's story I was amazed and hopeful to see he was having weekly drainages of his effusion. At that time Mishka was up to her 4th drainage and i was unsure if we were going to slowly starve her to death by doing more because that was the most any other cat I heard of ever had to have before they either died or got better. So seeing Blade in such good health after 2 whole years gave us courage to proceed even though I do not have details of bloodwork or diagnostics. His veterinarian is Dr Paul Crawshaw at the Wyandotte Animal Hospital in Wyandotte, Michigan.
"Forget the ridiculous amount of toys, I just want to sit in the basket!"
October 9 2012 Joni Swanson writes:
"He
will be 8 on October 30th, couldn't believe we were dealing with this at
his age, but other than his little belly, you would never know he was
sick. We have 5 cats and he is the most feisty. We have gone from once a week to once every four weeks, as of last
week.
The dr uses the ultrasound machine while using a catheter to
remove the fluid. Every once in a while they say he starts flipping his
tail and becomes vocal, but is a good boy for the most part. The fluid
removed is between 1/2-1lb...was 410cc, used to remove 300-400 per
week....when they bring him back, he acts perfectly fine. Jumps off the
table, is a little nosey, then goes to his carrier. Dr gave me some
medication to give him before i take him next time, said it will take
the edge off. Otherwise he hasn't been given anything. It is about $86
each time......don't even know how we did it financially 2 yrs ago when
he was going every week, guess I always hoped for a miracle.....it kept
me going. I call him my million dollar kitty. He gets 1ml of interferon
and 1ml of prednisone.The vet charges us $20 for the interferon (good
for 2 mths) and the prednisone prescription is $32. Also crush 250mg of Rutin, a dietary supplement vitamin, to put on a spoonful of canned food
2-3 times per day. Was told by another vet that I didn't have to bother
after he confirmed the FIP, but I continue to do what I had been for
the previous year. I could talk all night about my little
Blade.....sorry to keep blabbing......my heart breaks for all the babies
lost to this horrible disease."
"He is doing good....had 320 ml removed on Tuesday. He had a plateful of turkey and is napping now
Talked to the dr about the different vitamins I have seen and asked
about PI (polyprenyl immunostimmulant,). He said he would look into the PI, but said Blade is doing so
well, why change anything."
Blade
update: good news from visit on January 2nd 2013
"only 200ml was removed, down from 260ml removed 3 weeks
prior, ultrasound showed less fluid and Blade weighed the same as the
did after the 260ml was removed. Dr says he is an exception....just
can't figure it out, but whatever it is, it is working. I know FIP is
not curable, but Blade sure gives me high hopes! I also cut back on
prednisone and interferon, used to have no problem giving him the
medication, but when he started running and hiding from me, I wasn't
going to force it down him. Could the steroid cause more fluid buildup? I
don't know, but other than that darn fluid, you would never know he was
sick. He is the king of the house" Long live the king :)
“Some people don't really know enough to make a pronouncement of doom” ― Norman Cousins, Anatomy Of An Illness
Madiera is a year old kitty who had spontaneous resolution of ascites. She was diagnosed with wet fip end of march 2012 around 12 weeks of age.
It is lovely to read about a genuine recovery that demonstrates the bodies natural healing compared to healing that is often termed 'spontaneous' but where the patient has worked jolly hard at repelling the problem. I am reminded of Remarkable recoveries - a speech by Ian Gawler - he recovered from osteogenic sarcoma and his story kickstarted a holistic cancer cure movement in Australia. i think i read in Ian Gawler's biography "the dragon's blessing" something like spontaneous remission - there was nothing spontaneous about it!
She lives with Nicole Griffin-MacKenzie who sent this picture in to the FIP fighters Facebook group (our correspondance copied with permission)
August 19 2012
This is a pic from now, 5 months later and the fluid is still completely gone. ( she loves showers ) we are very blessed. Just wanted to share because I feel there is hope
NICOLE: She's not on anything just takes pedialyte 3x a day for her stools to stay normal. The first time she was tested by the veterinarian it was with a sample from the fluid in her abdomen, then dr Legendre requested a second test to be done ( due to the fluid disappearing ) and again the tests pointed to FIP , we were going to do the PI and that's why we were speaking to Dr. L but he stated to let it be if she is doing so well Still doing great ( knock on wood) October 8 2012
NICOLE: We got her in February, at 8 weeks so she will be a year next month. We didn't change her diet at all. We stuck with the same kitten food that she was on. The only thing we changed was giving her pedialyte. When we thought she had weeks to live I we were giving her a tablespoon of vanilla ice cream at night but that changed as soon as we noticed her abdomen going down. She was urinating a lot during this time ... Which I'm sure has nothing to do with it
ME: wow what brand vanilla icecream! who knows you may have stumbled onto THE CURE. i'm only half kidding. the urine was the fluid going out. what breed is she? there is 'spontaneous resolution' ie her immune system kicked in on its own; thymus gland is still there i think at 8 weeks, it is not so active in older cats. when did she get sick?
ME:i better explain my self about the vanilla icecream - if you read the anatomy of an illness as perceived by the patient by norman cousins and see what he did. i have been searching for the equivalent of funny things for a cat. icecream may be the thing.
Food does not come in a pyramid for Mishka, just - Noms or Antinoms. (nom = sound cat makes head down in plate of yummy food "nom nom nom") Strangely
curcumin extract. ground eggshell, the appallingly black fulvic
minerals, and Dr Wheatgrass extract which all cause my human child to gag are acceptable cat condiments.
Noms - fish, roast chicken, roast lamb, mashed pumpkin, Kraft cheeseslices,whey powder, raw egg yolk, grass and wheatgrass even though this sometimes makes her gag or even throw up (the kitty equivalent of alcohol? so nom i don't care about hangovers?)
Tish's list is of course the complete reverse - except for spirulina - evil green pond sludge which no one except me thinks is acceptable. Mishka will reject the entire plate of food if it contains a particle of antinoms the size of a nailhead.
So of course a raw diet is just what the doctors Addie (FIP research), Lipkin (virus hunter) Kremer (HIV expert below) ordered for our purebred princess. Ziwipeak (airdried meat - fits into the definition of a raw diet as it avoids high/low temp processing ) and raw eggyolk are the closest she gets to a primal diet.
The experts mention L carnitine which is the one amino acid I thought a carnivore would have trouble being deficient in. Turns out we can cook the nutrition out of anything;
" dog and
cat foods are extremely low in free L- Carnitine levels as compared with
that found in raw ground beef. Most pets are maintained strictly on
commercial pet food diets and are thus kept chronically deficient in L-
Carnitine. " Lack of Carnitine causes muscle weakness including heart disease. http://meowmeowmom.wordpress.com/2008/05/05/the-carnitine-conundrum/
Carnitine is easy to get as a powder - but the acidic form has a sour taste which cats loathe. If you cannot pill a cat who won't eat raw try QUINICARN chicken flavoured powder Supplement For Dogs & Cats "Supports Body's Defense Against Physiological and Metabolic Stress" cat dose 250 mg daily
Kremer's Nontoxic AIDS Therapy and Prevention
I am slowly reading a scholarly work on HIV/AIDS by Heinrich Kremer, 'The Silent
Revolution of the AIDS- and Cancer-Medicine' A complete summary of the book is available online - http://www.aliveandwellsf.org/kremer/it has the lowdown
on what kicks a system from th1 to th2 and how to prevent that; makes
so much sense, like a universal theory of disease. I cut to the healing section yesterday. it has
some reccomendations which may translate well to cats. the key is to
avoid oxidative stress and support the glutathione levels in the body; FIP cats have low plasma glutathione.
it is why dr addie wants us to add arginine to the diet for FIP as a
couple of teaspoons of raw red meat a week - again i'm researching precise
dose levels for supplemental powders as Mishka won't eat raw ( so much cheaper and easier if she would just eat the meat raw! Amino acid supplementation is fiddly - stuffing up ratios causes much more harm than good.)
NAcetylCysteine NAC another key antioxidant in the glutathione chain may also be useful both as treatment and preventative. "N-acetylcysteine (NAC) is a chemically modified form of the dietary
amino acid cysteine. Cysteine and NAC contain sulphur, which is key to
protecting the body from damage by oxidation. Other sulphur containing
antioxidants include alpha-lipoic acid and glutathione. Glutathione
levels are considered the most reliable indicator of the body's
resistance to oxidation, and NAC plays a role in glutathione metabolism.
While touted by many supplement manufacturers as a precursor to
glutathione, NAC probably has more of a sparing effect. That is, it
neutralises oxidants in place of glutathione, allowing glutathione
levels to be maintained."http://www.manorvets.co.uk/pet-sub-sub/972-n-acetylcysteine/
Step 8: Get spouse to lie on cat with head just visible from below armpit. Put pill in end of drinking straw, force mouth open with pencil and blow down drinking straw. Step 9: Check label to make sure pill not harmful to humans, drink glass of water to take taste away. Apply Band-Aid to spouse's forearm and remove blood from carpet with cold water and soap. - from HOW TO GIVE YOUR CAT A PILL IN TWENTY EASY STEPS
< Some cats are Zen masters. Sub cutaneous fluids seemed sooooo easy from the video
demonstration by the very pregnant lady vet (nope). We are talking
about a longhaired cat that thinks fur brush is medieval
torture device so the road to health was always going to be a little
extra challenging. She didn't even like the pentoxifylline transdermal
cream (pea sized blob rubbed into ear twice daily) The only patient more
uncooperative than the cat is
my husband - the doctor.
Fortunately Mishka eats size 3
capsules pretty reliably like kibble if we put them in a teaspoon of
moist food served as the entree when she is hungry. Most supplements
have to be downsized anyway - get empty gelatine capsules. More excellent tips on medicating cats from Joel Kehler. Here's one method for getting the little pills down without upsetting kitty. (although it looks like i faked it she did eat the pill!)
What's worse than pills? Liquids. Even 6 mls is a lot of liquid for a cat if it tastes bad. Their natural response is to drool like Niagara Falls and squirting too much in fast may choke kitty. It doesn't actually need to be medicine. The early days of FIP with a dehydrated, inapetant cat required some syringe feeding of electrolytes and food. We found the process so distressing initially - and then we discovered the magic of soothing music. It still wasn't a picnic and if she hadn't perked up within 48 hours we would have pulled the plug. Here's ahow to give liquids video from Lauren via FIP fighters on facebook. Her cat doesn't look impossibly upset by the whole process. "One thing I would like to add that Brian (giving the syringe) did during the video: It looks like when she turned her head he was giving the syringe head on/under nose. Try and avoid this at all costs. It's a lot easier on the cat if you do it on the side and they naturally open their mouth when you do it there.Here's a few pointers:- Smaller syringes are MUCH easier to use. If you're doing this long-term always keep a few on backup because they do tend to break a lot.- If the medicine/food is cold, you can take the syringe in-between your hands and hold it/roll it for a few seconds to warm it up.- If your kitty is nervous be sure and massage the back of her neck and talk to her while you're administrating the medicine/food.- This is A LOT less of a mess but still keep a napkin nearby. You can still make a papertowel bib if needed.- If your kitty doesn't like being on her back AT ALL you can still do this technique but have her on her tummy instead. Still go from the side and still hold her close, it'll make her feel more safe and secure. You don't have to grab the scruff hard. It's only for a little bit of control and comfort on her end. I'm fully against hurtful techniques against cats even if a vet is doing it to get medicine in. I can assure you this in no way harms your cat and it should be instinct for them to accept it.Be sure and give your babies lots of love and kisses after this and possibly a treat if they're not too stressed over it so they associate this with some kind of positivity instead of a majorly hated event."
Polyprenyl
immunostimulant is a taste issue for some cats, the insert says 1%. It
was initially tested via injection - now it is approved for oral use so
unfortunately the company are refusing to advise on injection except to
say it will sting as it is hypertonic. After a somewhat traumatic first
effort when i tried mixing the entire dose into Mishy's lunch we settled
on a pattern of putting it a ml at a time into a well in a level
teaspoon of moist food and carefully pushing this shut and serving it
piecemeal to a very hungry breakfast kitty. Any higher ratio leads to
rejection. If she starts to look satiated we stop and start again an hour later -
she is sometimes full after 3-4 mls. A heaped teaspoon is actually a
prey sized meal for a cat. The PI is only stable after mixing with food
for about 30 mins and must be kept out of the light. Video of how we do it
here is Tanja's unhappy experience of using PI with her cat Sampson :
I
chose to go with PI as I was looking for that miracle that would keep
Sampson alive a lot longer, and the successful cases looked better on
paper than the interferon; unfortunately for Sampson he threw a clot and
with everything he was battling at the same time I could not morally
try to make him recover from that plus the FIP.
Personally
I do not think the PI was working for Sampson, before he threw the clot
I had already decided to stop the PI treatment, his belly was also
starting to feel quite fluidy and I believe it was transforming into the
wet form. It is a gamble and I do and don't regret using PI. If I
hadn't I would always wonder but the process of giving him the PI in
such a large amount by mouth was quite stressful for him and I wish we
hadn't spent our last days doing that.
Sampson,
he was honestly the furry love of my life and miss him so much that it
feels like a piece of me has been torn to shreds, if i could go back and
they could offer me an injectible, absolutely without a doubt i would
do that, giving it orally was the worst part of the whole thing, no
matter how i did it.
Videoing the method could be good, i was
giving S-man the full amount in one go because he wouldn't eat the food
with any on it, and i didnt want to give him the meds more than once in a
day because i felt bad making him do it again, we just had a big treat
of chicken loaf afterwards.
Injecting sub cutaneous vitamin C was actually orders of magnitude less stressful than a misguided attempt to use ascorbic acid in her food or as a syringed supplement. (note: Sodium ascorbate though is virtually tasteless to a cat.) Although it must have stung like a bee, it was quick and we were forgiven eventually. We decided 4 shots only after the IV was removed to taper the dose down and give her the best start at the beginning of her illness. Mishka now gets interferon by injection. Actually it is knowing the routine that makes it unstressful - shot and then noms. It really helps to be given at a consistent time and the same 'medicine location' not used for sleeping or feeding, held by her bff Michael. She even stays relaxed with him in the car and at the vets.
“There is nothing like looking, if you want to find something. You certainly usually find something, if you look, but it is not always quite the something you were after.” J.R.R. Tolkien
The long words really get to me sometimes "Bovine dialyzable leukocyte extract"? Is that a nice name for bloody extract of squished cow? There seems to be a possibility of a scam in the supplements labelled 'transfer factors' - some FIP cats are getting http://transferfactor-4-life.com/thesecretoftransferfactors.aspx
I think however there is legitimate research: As Prof Lipkin says - raw meat is full of goodies!
http://www.sciencedirect.com/science/article/pii/S156757690400219X
Bovine dialyzable leukocyte extract (bDLE) is a dialyzate of a heterogeneous mixture of low molecular weight substances released from disintegrated leukocytes of the blood or lymphoid tissue obtained from homogenized bovine spleen. bDLE is clinically effective for a broad spectrum of diseases. To determine whether bDLE improves survival and modulates the expression of pro-inflammatory cytokine genes in LPS-induced, murine endotoxic shock, Balb/C mice were treated with bDLE (1 U) after pretreatment with LPS (17 mg/kg). The bDLE improved survival (90%), suppressed IL-10 and IL-6, and decreased IL-1β, TNF-α, and IL-12p40 mRNA expression; and decreased the production of IL-10 (P<0.01), TNF-α (P<0.01), and IL-6 (P<0.01)
in LPS-induced, murine endotoxic shock. Our results demonstrate that
bDLE leads to improved survival in LPS-induced endotoxic shock in mice,
modulating the pro-inflammatory cytokine gene expression, suggesting
that bDLE is an effective therapeutic agent for inflammatory illnesses
associated with an unbalanced expression of pro-inflammatory cytokine
genes such as in endotoxic shock, rheumatic arthritis and other
diseases.
Hoping the ever helpful Dr Norris will comment soon. The amazing claims for some supplements are worse than hair product ads. It pays to be skeptical and do your due diligence though the horrible knowledge that FIP is a rapid disease means this is a real dilemma. In hindsight I would like to erase the two week delay popping homeopathic drops on an intermittently febrile cat while I tracked down and checked out feline interferon (FOI). Hence I hope this blog will be helpful to others in some way rather than just more to read and worry over.
" A great many things in my life would be different if only I could open the door to the refrigerator. "~ Henri, le chat noir
Grains and carnivores - not a happy mix
It is nice to have Mishka back to normal - hunting around the house in the wee hours for snacks ... bang bang bang at 4 am opening cupboards, finding her in a pile of kibble ....
oh crap - waiting for the sound of puking
She was vomiting again on
tuesday evening / wed morning. Perhaps it was a bit of plastic from chomping into the loaf of fruit bread on the bench, or the bread itself. Thankfully settled by midday but for many hours I thought it was all over though she is
stronger; still playing with me after 4 chucks! took five to take her
down a bit, and she remained well hydrated. Previously one or two chucks
made her a limp fur rag. She was examined and cleared by our vet for
continued treatment, so drained again wed pm and perked up straight way
as usual - so we put it down to scoffing kibble accidentally left out
for the other cat on top of the illicit snacks. We are not serving even a mouthful of this junk
food even as a treat anymore though she does miss it since Friskies Indoor
was all she ever ate when she came to us.
Mishka wasn't particularly
fippy belly leading up to the vomiting so it caught me by surprise. Might be
magical thinking but let's pretend the fluid is slowing down marginally. After a week we
only drained 465 mls. The time before we took off that much after only
five days. No hairball has come up, and also no grass yet even though she
has also scoffed her nommy new wheatgrass today which astonishingly seemed to make her feel better almost immediately.
Firstly i stopped the curcumin and pentoxifyllinecream
since they can both upset the tummy with no difference in Mishka's
constitution except she is happier ( the pentoxi cream was was getting
increasingly unsettling applied even just twice daily instead of the
required three. i wasn't going to renew the prescription as it hasn't
made huge inroads into her disease for the emotional cost - just tried
replacing it with curcumin as the anti-inflammatory. We haven't missed
the prednisolone.
Curcumin extract suggested by a
friend was originally rejected because i thought it would be hard to
dose ( not true ~ she likes the flavour or ignores it but it stains fur
pink! ) and I have read it may be immune suppressive although possibly in
away that is ok For starters it hammers the TH1 and TH2 systems even handedly http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810449/
Too
many long words - waiting on comment by Dr Norris. We can't get Thorne brand
Curcuvet in australia but herbs of gold sell an easy to get product
containing the same bioavailable Meriva extract Thorne uses.
And still waaaiting for the customs clearance to get PI - come on Santa!