Pharoah tries stemcells for FIP and the cure for FIP is found!

One success story at a time

With FIP there is no point being conservative except for the sake of the cat's comfort. So it was no surprise to hear that yet another innovative therapy is being tried - adipose stemcell therapy for dry FIP. The cat is called Pharoah and his vet is Ed Pattison of City Vets, Exeter UK https://www.facebook.com/cityvets/photos/a.128542133823284.22418.128403317170499/957763074234515/

But how interesting is this - the vet who pioneered the use of adipose stemcells for arthritis in dogs in australia, Simon Craig, was the same chap who cured Dusty of wet FIP - see survivor's page

and how dull and unsexy is this - Hip arthritis in dogs by the way you can simply prevent with adequate vitamin C and a proper diet.
http://oneradionetwork.com/health/dr-r-geoffrey-broderick-world-renowned-veterinarian/

Dr Belfield has the word on vitamin c in animals and was kind enough to answer my emails when Mishka was diagnosed. he did try it for FIP of course and it was the one thing he had no success with after it was established :( That's what we are up against.
I have NO DOUBT this is the same with FIP - we can prevent it  simply - no rocket stemcell science required and finally someone in authority is brave enough to say it 

"The best treatment for FIP is not to get it in the first place: if you are going to buy a pedigree kitten, make sure your Vet sends a blood sample to the University of Glasgow Veterinary Diagnostic Services to get a certificate saying that the kitten tested negative for feline coronavirus (FCoV) antibodies: we need to put consumer pressure on bad breeders and reward good ones." Dr Dianne Addie rocks! http://www.theexeterdaily.co.uk/news/local-news/exeter-vets-pioneer-stem-cell-treatment

- see prevention page

• stop inbreeding 
• stop crowding 
• stop malnourishment of starvation and stop feeding COOKED CRAP & KIBBLE to cats - they weren't designed to eat cereal; they are not birds.

Tomten - Where do you go when your cat has stumped all the vets?

A: a cat specialist - case solved by Dr Plotnick! http://manhattancats.com/
The first blog post on I wrote on his case was the Winter Tomten "Yuletide " the midpoint of winter - the cosmic balance between life and death". I feel like we are poised on such a tipping point - and i cant help thinking being in the southern hemisphere the december solstice signals the descent." If you want to follow his story in graphic detail use the labels to find the other posts but now for the news i should have updated months ago! Tomten was originally thought to have FIP around the same time as Mishka. He had already started feline interferon so I drew a lot of strength from the kindness of Cassie answering my emails 2 years ago. For Cassie the drug was a really really big ask as it is hard to import to the USA as well as super expensive. 

"He who asks a question is a fool for five minutes; he who does not ask a question remains a fool forever." - Chinese proverb

 So glad her persitence paid off: June 2014 Cassie posted -

Finally a possible explanation for Tomten's illness. Ok I have truly crossed over to crazy cat lady. While making Tomten's next appointment for his Cardio check up I began feeling frustrated that he still has no diagnosis. So I broke down and submitted an e-mail to Cat Fancy magazine's ask the doctor. I felt a bit silly but figured what could it hurt? 

My 7 year old Devon Rex has stumped all the vets he has seen. 2 years ago he stopped eating, started throwing up and was hiding. An emergency trip to the local ER showed that he hadgranulomatous tumor in his intestines. An aspiration of the tumor ruled out lymphoma and based on his blood work he was diagnosed with dry FIP. He was put on feline interferon and methyl prednisone and sent home to die. Only a “miracle” happened and he appeared to get better over the course of two months. Three months after diagnoses scans showed that his tumors had disappeared through his lymph nodes remained swollen and abnormal. 12 months after the first tumor appeared he stopped eating again. Scans showed 3 new granulomatous tumors one of which was in danger of perforating his bowel. At this point his vet moved him to an excellent large regional vet hospital. They consensus was that he didn’t have FIP (based on his longevity). Since he was no longer responding to the feline interferon the thought was to do surgery to remove the tumors. All 3 tumors where removed in a double bowel resection and subsequent gram staining of the tissue was negative for FIP. He appeared to recover for a bit and then went into a tail spin hiding and not eating. He was placed back on the methyl prednisone and within a week was recovering once again. 3 months later he developed an ear polyp and infection and lost his balance. A month of antibiotics and dedicated ear cleaning and he recovered much of his balance but his counter surfing days where behind him. When he was being evaluated to remove the ear polyps it was discovered that his heart had become greatly enlarged and he was in heart failure. We made the decision to leave the ear polyps and focus on managing his failing heart.

Tomten has been lucky to have better care than many human beings and we are very grateful to his vet teams, who have given him an additional two years of life. The vets have all been unanimous that what ever is causing his health problems is an unknown and perhaps is some sort of an autoimmune disease? While we have tried to make peace with the fact that we will probably never know what is wrong with him its hard not to wonder if we took him somewhere else would someone know what is causing his condition? And could we do anything to stop it other than to treat each symptom as it comes up.

Dr Plotnick's Reply:

I think the ear polyps and the heart disease are separate issues. Devon Rexes are at increased risk of developing hypertrophic cardiomyopathy, which is the heart disease I suspect he has. As for the intestinal disorder, it sounds like your cat has granulomatous enteritis. This is a mysterious illness. Inflammatory bowel disease is a common disorder in cats. With IBD, most cases are due to infiltration of the intestines with either lymphocytes and plasma cells, or with eosinophils. These are types of inflammatory cells. Every now and then, we see a case that doesn’t fit into this pattern. We see what they call granulomatous inflammation. In these cases, the intestines are infiltrated with lymphocytes, plasma cells, macrophages, neutrophils..a whole mishmash of inflammatory cells. It often affects a discrete region of the intestine, rather than diffusely infiltrating the intestines. (Diffuse infiltration is the more common scenario.) (The disease has sometimes been called “regional enteritis” because it affects a discrete region of the intestine). FIP likes to cause granulomatous inflammation, but not all cases of granulomatous inflammation are due to FIP. When granulomatous inflammation is seen on an intestinal biopsy, the specimen should be stained with a special stain that detects coronavirus in the tissue. If the stain comes back positive, the cat has FIP, and the prognosis is terrible. If the stain comes back negative, it rules out FIP. However, the prognosis for granulomatous inflammation in the intestine is unknown. It’s a mysterious disease that no one has really figured out. Some people try steroids, and they work for some cats, in some cases. Other people suggest surgically removing the affected area. There are no big case studies of cats with this type of enteritis, so we don’t really know what the best treatment is. Unfortunately, I think the best approach is the one you’ve been doing, i.e. treat the symptoms as they come up. With him having heart disease, steroids are not recommended because steroids expand your cat’s blood volume, which can put a strain on the heart. I’m not sure how you would treat another bout of granulomatous enteritis if it were to develop again. Good luck with him. I hope he does well.

Dr. Arnold Plotnick

I've asked Cassie for an update - i know some on the facebook group had reccomended the raw diet as she was investigating IBD - Irritable Bowel Disease.  

PS. I love Dr Plotnick's idea of a cat only vet - cats hate the fuss and stress of a regular clinic full of dogs. Poor Mishka's worst moments were not from FIP so much as the 'system' - I won't spoil this feelgood post with the details of that - contact Dr Plotnick http://manhattancats.com/

Ilana's cat survives with wet FIP

 I don't stop in here now except to bring the good news stories - yes in amongst all the heartbreak there are SURVIVORS!!! and as always much love and caring from people like the tireless Oscar Birman who will hold your hand across the internet on the FIP facebook page where we were told about Illana's cat. They live in France where Dr Addie is now ( you can read about her protocols on treatment page ).

Ilana Dagan My cat had the wet FIP and she takes prednisolone every day and interferon (for human, less expensive).I told my vet about the web site of dr diane addie who wrote about FIP and we found there the right treatment for my cat.She had no more fever,no more fluid in the abdomen and she gained back her weight,it was 8 months ago and she is still very fine! ~ 15/10/14 https://www.facebook.com/groups/fipfighters/798509346862004

I've asked Ilana for more details and a photo and she agreed although I still haven't got these - hopefully these will be sent and we can keep tabs on how her cat fared weaning off the drugs.
Please make sure to read my notes on diagnosis, treatment and the actual survivor case histories, where you will find links to notes about Dr Addie's protocols, and do touchbase with the FIP facebook group for support no matter what the outcome.
Wishing much peace and love to you,
Carolyn

Update Jan 2015 Ilana's cat i think is still ok but I've messaged her again for more info.

Tigger

"I'm so happy I could bounce!" ~ Tigger

This is a story I got from one of the FIP yahoo groups. It has stayed in the drafts folder of this blog for over a year. I didn't manage to contact Tigger's mum for more details, a picture and so on. Post is copied verbatim as I expect Tigger's mum wants the story out there. So sadly I don't have details of diagnosis, no bloodwork - that's a caveat, it may not be FIP but it's hard to think of what else could have made him so sick for 6 weeks; my notes say wet FIP.  I can see the precipitating immune suppressing causes are pretty common ones. The move was big one as I recall; I think Tigger had to take a plane ride and was received at the other end unwell. He is a little older than usual. Most importantly Tigger's successful treatment has commonalities with other survivors - antibiotics combined with IV fluids and an immune stimulant - in this case interferon ( i think probably it is feline interferon since this cat is in Europe. ) special food (again wish I knew the details!) and intense daily attention.

Hi. I have a rambunctious male 5 year old cat. His name is Tigger. 5 months ago, I moved to Turkey. He had a shot for Luekemia (sp prob wrong) Anyway BAD idea. Don't ever get your cat a shot for this without getting him tested for the corona virus. I'm not sure if I spelled that right either but it's easy enough for you to google.

Anyway, the move and shot sent him into full blown FIP. His eyes were rolling to the back of his head, sky high fever, skin and bones, boy did I thought he was a goner. We started interferon and vitamins, antibiotics and Iv every day for a month and a half. Each day I spent 2-3 hours at the vet. 5 months later, he is alive and fat and happy. Each day I give him 2 vitamins. One in the morning and one at night. And they have garlic in them, yes, garlic.

If you make a serious commitment to keep your cat alive, I believe you have a pretty good shot of beating this with the help of interferon. I also give him food for sensitive systems and NO treats!! TReats do not help any cat. I have a second cat that seems to be fine and probably live to be 20. Tigger is living on borrowed time but I treasure ever extra moment. I also keep their cat box VERY clean. 2ce a day I clean it. My heart goes out to all owners with fip cats. It's heart wrenching, I know.

My other thought, a year of case history reviews later, is that I feel vets are not paying enough attention to fluid and salt (electrolyte) managment in FIP cats. Sick inapetant cats are easily dehydrated as they are desert animals designed to get most of their fluids from freshly killed prey. Vets seem to devote all the owner's resources to diagnostic gymnastics while their patient slips away from under their noses. Any reasonably sick human wheeled into an ER would be instantly hooked to an IV while this is worked out.
Also on the home front I doubt this cat was left to waste his remaining energy dragging himself to a litterbox too far, up a flight of stairs to the bedroom or being needlessly stressed by a bath (this is not sarcasm - I do actually know of someone who went to the trouble of getting PI then bathed their FIP cat. Predictably it took a downhill turn from there and is not listed on my survivors log.)

picture by felicia ruiyi - deviantart

Murphy - misdiagnosis of wet FIP

Mischievous Murphy from Germany is a kitten successfully treated for bacterial peritonitis which was initially mis-diagnosed as FIP in April 2013 when he was 8 months old. Fortunately Jennifer did not give up. She found a second opinion from another vet, who although she could not rule out FIP even though his abdominal fluid tested negative for coronavirus, committed to save him and went for treating the treatable in the face of uncertainty. Murphy was given Suanatem (Metronidazole and Spiramycin) and recovered quickly.

This continues the series on misdiagnosis. Please make sure you check out Dr Addies's diagnostic algorithm's for FIP on treatment page before losing hope. And donate to FIP research which is working towards a fast and reliable diagnostic tool. In australia this is University of Sydney with Jaqui Norris.

Preventing FIP is simple

"God grant me the serenity to accept the things I cannot change, the courage to change the things I can, and the wisdom to know the difference."Reinhold Niebuhr

What really really makes me mad about FIP is the complacency in the cat owning community since it is supposedly a coronavirus mutation confined to the unlucky individual cat and furthermore not transmissable to humans; FeCoV (feline coronavirus) is an oral fecal thing and has a very short persistance outside a host therefor theoretically easy to beat. No FeCOV = no FIP. Worse things have been banished with no more exciting weapons than soap, clean water and flushing loos.

"FIP is pretty rare in housecats who are not exposed to other cats, occurring in roughly 1 in 5000 cats in this situation. FIP is fairly common in catteries in which feline coronavirus carriers are present, occurring in about 1 in 20 cats in this situation." 
Read more: Feline Infectious Peritonitis( FIP) and Feline coronavirus (FeCoV) - VetInfo 

What really really scares me about FIP though is the breeding of virulence by letting it cycle multiple times through kitty hosts who are unaturally confined indoors with an abnormal number of other potential hosts, who are to boot, probably immune suppressed through poor diet and inbreeding. "Wu Lien-teh, moreover, suggested that virulence increases in the course of an epidemic. Dongzheng Yu conducted a series of experiments in rats to test this idea. He injected them with a strain of plague from wild rodents; the injected rats were not easily infected and died slowly. Next, he withdrew plague bacteria from those rats and injected it into others, and on and on. Eventually, this serial passage produced a plague strain so lethal that rats injected with only a tiny amount died rapidly, suggesting that the strain's virulence had markedly increased." http://discovermagazine.com/2001/nov/featblack#.UaXtboLC--k

The knee jerk reaction, massive culling, as happened to the civet cats in China during SARS, is probably counterproductive - civets have low immunity anyway, why ruin the genepool further?

 "The last thing we should do is to take it out on the bats, because the evidence suggests that they have carried this coronavirus for thousands, perhaps millions, of years; only recently has it emerged in a big way, and it was human behaviours that made the difference." http://evolution.berkeley.edu/evolibrary/news/060101_batsars

We need to change our behaviours now, because this is the one thing about FIP we can control while still dreaming of some miracle pill - and it's entirely DOABLE http://www.dr-addie.com/Prevention/PreventionS1.htm#How to eliminate FCoV infection from a cattery

Leap of Faith

"Healing takes courage, and we all have courage, even if we have to dig a little to find it." - Tori Amos

I wrote this just before Mishka died on Feb 1st but I've decided to post it unchanged. Update: a few edits and see the comment from Dusty's mum below!
--------------------------------------------
Dusty is the reason we are treating Mishka. Dusty survived wet FIP of the lungs in part thanks to injections of feline interferon and oral prednisone in 2007. I first wrote about him in a post about Hope http://onecatlife.blogspot.com/2012/10/hope-is-black-swan.html

Virbac sent me the case history and amazingly here was a cat I could believe in because I knew the vet practice in Sydney (I think my mum even took our old cat there on occasion. Chloe was a stray my brother took in who lived to be 17 on a commercial diet without ever getting regular vaccinations btw)  so I phoned the vet, Simon Craig who verified the cat was still kicking and had made it off the interferon. Based on Dusty's outcome we did the math and decided we could afford the treatment on the basis of expecting a dead cat or a cure in a little over two weeks - but there you have it, each case is unique and Mishka has not progressed as well - but she's not dead either, so the budget is completely blown by five months worth of extra drugs. We have apparently converted an acute illness into a chronic one - as allopathic medicine does so well.

Possibly due to her more advanced disease ( she has abdominal FIP as well) her own genetic challenges (she is a Birman, Dusty is a Scottish Fold) or that two week delay or not using the steroids first up. Dr Addie does mention in her wet fip case study, which I only recently read, that the wet FIP response to FOI is higher for cats with FIP of the lungs, and doesn't seem to work as well on abdominal FIP.

My suspicion is this is because abdominal FIP can be cryptic for longer in that area without causing distress. Mishka had abdominal fluid for a few weeks to a month perhaps before we knew she was sick.

It wasn't until her lungs really filled up that we rushed to the vet. Perhaps she was also dehydrated somewhat and thirstier than usual. Here she is the night before, mucking about and looking ok:

She may have been sick for much longer as the earliest signs are so hard to detect as abnormal, if indeed they were - she started being more sleepy (thought that was natural as a cat growing older and not being a kitten any longer), more cuddly and purry - well she got to know us and that's a nice thing, she was very hungry and insisted on 4 am snacks - well she's a growing cat. She got so chubby she was stuck in her cat door - that was cute (ok my son had at that stage twigged something was up. "mum Mishka is not a cat anymore" ? "Definition of a cat - fits anywhere the head fits" ??!!! )

Definition of a cat - fits anywhere the head fits

 Mishka's Leap of Faith

 
and so we followed the example of Dusty. I feel like a cartoon character that's headed over the cliff - can't stop running to look down now or gravity will reassert itself. Hoping to make it to the other side on pure momentum. Courage kitty - leap!

Die another day - Toby and 0029

"I'm checking out. Thanks for the Kiss of Life." ~ James Bond (Die Another Day)

oh heck - just as the rest of her seems to be rallying kitty has a 'funny lump' under the skin which is possibly getting bigger. The vet is ignoring it strenuously and I'm not thinking straight - perhaps I should have jumped on it last week and investigated while she was under for the drain. The thing neither of us want to face is the prospect of a malignancy.

Seems she is simply dying more slowly, as our vet puts it - or living to die from something else like Toby - who was an uneutered Tom cat from Woodstock Ontario Canada. Toby lived the bachelor lifestyle, out partying every night and returning home in the daylight hours for food. When he got wet FIP he survived due to the ministrations of his owner, homeopathy and a change of diet (he stopped Taste of the Wild dry food and the pokeweed prescribed by a naturopath amongst other things); Toby fast tracked from having a FIP belly drained in August 2011 to normal function, including the partying, by September a few weeks later. He had places to be and cats to see - ladies to romance, guys to fight I guess and in April 2012 walked off into the night, sporting a swollen leg from an encounter of the 007 kind, never to be seen since by his human, Monika.

There was similar kitty, known only to me as "29" who was one of the original cats on the Polyprenyl Immunostimulant study. 0029 had dry FIP with neurological symptoms, who during treatment got well enough to get back to the killing business but met his match in a coyote. "when he was sick he was hanging around the house, once he started feeling better, it was hunting again, it was bringing little presents to the owners on a regular basis." ~  Dr Legendre WINN Feline Symposium transcript

But of course I am the eternal optomist. Unlikely things happen such as Miko the red burmese being reunited at the grand old age of 17 with his family in Essex, UK after a staggering ten years AWOL thanks to his microchip. Who knows, Toby is merely MIA he may reappear into Monika's life somewhere down the road.

from humortrain

Back from the brink - Lilly

"If you are going through hell, keep going." - Sir Winston Churchill

Lilly and Alethea's journey shows it is possible to come back from the brink but it is only if the owner will devote to two hourly nursing including horrible syringe feeds for as long as it takes. If one can't do that i think don't bother looking for miracle drugs - immune stims need time and basic building blocks in the cells to work a miracle.

"I initially gave Lilly 5ml of PI twice a week. Honestly she seemed to improve in the first week so much I was shocked." ~ Alethea via facebook January 16, 2013

"I want to give an update - if only to give others much hope. In November (2012) my cat Lilly who is about a year and a half old was diagnosed with dry FIP. I was told based on her condition that she would be dead in a few days. She was not eating and I was giving her subcutaneous fluids hourly.

I was told by my vet that the meds are probably not gonna work and that if Lilly recovered it was because she does not have FIP. I don't know really - all the test indicated she did. The uveitis in her eyes was so severe and she was dying right before my eyes.

I gave her her first dose of PI on November 18th and continued to force feed her with a syringe this high end prescription cat food. The food is a/d critical care and I would mix it with water and give it to her by syringe at least 1/2 a can a day.

After a week of being on PI and me feeding and caring for her around the clock she began to show improvement! I was hopeful. Lilly had what looked like uveitis in her eyes and it began to clear. She started eating a little on her own. I continued feeding her by syringe [twice a day] for one month even though she was eating on her own - and giving her the PI.

The uveitis and her blood filled eyes cleared in two weeks from the the time she started the meds. I gave her two [5 ml doses] a week for about a month and a half but now it's only once every seven days. I only give it to her once a week now because a. she seems completely well and b. it's insanely expensive. Lilly weighs about 7 pounds - probably 8 now because she has gained weight.

She hates the taste of PI - but I have learned to give it to her quickly and make sure she gets a treat after. 

Lilly is now 100% - she seems as if nothing ever happened. She runs around and plays just as she did before she got so sick. I pray for her every day that she will live a long and healthy life with me - and so far it looks good.

Best of wishes to all of you - it is so hard to watch the animal we love so much get sick. Just a side note - Lilly was not on steroids except for maybe a week and I never gave her any antibiotics either when she seemed to have a cough. I also took her in for IV fluids in her veins every time she sunk to near death so I could manage her condition better. The little hairless spots on Lilly's leg is where they shaved her for the iv:)" ~ compiled from two Facebook posts from Alethea January 2013

To really fight FIP tooth and claw on behalf of a kitty who really doesn't understand is a hard decision as the outcome is far from certain - Sampson's owner sort of regretted making him miserable with the PI. Others who have ultimately lost their kittens have as well. I can only say whatever happens be kind to yourself, forgive yourself everything and be at peace. When I look back I will look all the way back and remember the happy times, for there were many.

Paloma

"Panic plays no part in the training of a nurse." ~ Elizabeth Kenny

Paloma is a blue cream Persian named after Picasso's wife. We like to name our cats after artists. 

This lovely little cat is alive and well thanks to an article her family came across in a cat magazine about Polyprenyl Immunostimulant which she showed to her vet and careful dedicated nursing.

"I am posting this success story on behalf of my mother, Marilyn Schmitt. Her beloved cat, Paloma, first got sick with FIP at only 6 months of age. Things were touch and go for a long time, and we didn't think we would have Paloma for very long."

"We got her through those 6+ months by hand feeding her and wrapping her in ice blankets to get her temperature down. She also had a strong will...her sickness was sporadic prior to starting the PI." 
 
"When Paloma was over a year old, however, she started this treatment, and it has made all the difference in the world. She has been thriving on the medication for 13 months now, and this once listless cat now has ample energy for her repertoire of favorite activities that include playing with any toy that is a ball, playing a variety of games on "her" iPad for as long as the parents will let her, and being brushed, surprisingly enough. She has a new lease on life, and we are very grateful that Paloma had the opportunity to receive this treatment."

"Although she is now thriving, she still begs to be hand fed."
 
and yes there are interspecies electronic tablet games for cat v. human  free to download from http://gamesforcats.com/ 

Frank

"Life isn't about waiting for the storm to pass...it's learning to dance in the rain. " ~ unknown

This is Frank, a three legged Canadian alley cat who is going through treatment with PI for dry FIP.

Frank has started PI back in April 2011 on the Winn Foundation Study by Dr. Legendre. Here's his new family's report from Jan 2013.

"In the summer of 2008 Frank was found in an alley by some very kind people. He was taken to a vet clinic as a very sick little boy with a fractured hind leg that was very infected, unfortunately they could not afford to care for the kitten and relinquished him to the clinic for care. The vet clinic took excellent care of this little boy setting his leg and nursing him back to health. 

Soon after he was well enough to leave the clinic we were asked to foster him. Frank came into our home with a cast on his back leg but full of energy. We had 4 dogs at the time but he fit right in, he soon became the boss of the house. Soon after his cast was removed Frank began to limp again. He was brought into the clinic to investigate and it was discovered that the infection had spread to the bone and the only solution was to remove the leg. After his surgery he returned to our home, by now we couldn't imagine life without him and the decision was made to make him a permanent part of our family. He was as active and playful as ever even playing with our miniature schnauzers. 

In the winter of 2011 we noticed that Frank had lost weight and brought him to the clinic for examination. He was diagnosed with dry FIP. Thinking it was a death sentence for him we were prepared for the worst but desperately looked into treatment options. Dr.Kremeniuk at Park Pet Hospital found out about a drug trial for cats afflicted with this terrible disease and Frank was accepted into it. Since he has been on the PI he has returned to his normal self and we are so happy! Frank loves to go camping with us in the summer, he wears a harness and eagerly explores the campsite. He is so loved by the whole family and we are so grateful for PI giving him a second chance at life. He is a fighter and is determined to live as long as he can. Thank you Dr.Sass and everyone involved with PI for saving his life".

I'm not yet sure if Frank is still on the PI and at what dose. He's been through a lot and he's obviously determined to enjoy life to the full - thanks to his wonderful new family and vets for giving him that chance! Goodluck to you Frank.

Madiera

“Some people don't really know enough to make a pronouncement of doom” ― Norman Cousins, Anatomy Of An Illness

Madiera is a year old kitty who had spontaneous resolution of ascites. She was diagnosed with wet fip end of march 2012 around 12 weeks of age.

It is lovely to read about a genuine recovery that demonstrates the bodies natural healing compared to healing that is often termed 'spontaneous' but where the patient has worked jolly hard at repelling the problem. I am reminded of Remarkable recoveries - a speech by Ian Gawler - he recovered from osteogenic sarcoma and his story kickstarted a holistic cancer cure movement in Australia. i think i read in Ian Gawler's biography "the dragon's blessing" something like spontaneous remission - there was nothing spontaneous about it!

She lives with Nicole Griffin-MacKenzie who sent this picture in to the FIP fighters Facebook group (our correspondance copied with permission)

August 19 2012

This is a pic from now, 5 months later and the fluid is still completely gone. ( she loves showers ) we are very blessed. Just wanted to share because I feel there is hope

NICOLE: She's not on anything just takes pedialyte 3x a day for her stools to stay normal. The first time she was tested by the veterinarian it was with a sample from the fluid in her abdomen, then dr Legendre requested a second test to be done ( due to the fluid disappearing ) and again the tests pointed to FIP , we were going to do the PI and that's why we were speaking to Dr. L but he stated to let it be if she is doing so well
Still doing great ( knock on wood) October 8 2012

• 

  NICOLE: We got her in February, at 8 weeks so she will be a year next month. We didn't change her diet at all. We stuck with the same kitten food that she was on. The only thing we changed was giving her pedialyte. When we thought she had weeks to live I we were giving her a tablespoon of vanilla ice cream at night but that changed as soon as we noticed her abdomen going down. She was urinating a lot during this time ... Which I'm sure has nothing to do with it

  November 27, 2012
• ME: wow what brand vanilla icecream! who knows you may have stumbled onto THE CURE. i'm only half kidding. the urine was the fluid going out. what breed is she? there is 'spontaneous resolution' ie her immune system kicked in on its own; thymus gland is still there i think at 8 weeks, it is not so active in older cats. when did she get sick?

  November 28, 2012 at 12:09pm
   
• ME: i better explain my self about the vanilla icecream - if you read the anatomy of an illness as perceived by the patient by norman cousins and see what he did. i have been searching for the equivalent of funny things for a cat. icecream may be the thing.

  November 28, 2012 at 12:11pm
   
• 

  NICOLE: I think it was hood Boston vanilla bean

  November 28, 2012 at 1:03pm
  
  Madiera was still well and taking her 3xdaily pedialyte when Nicole sent me copies of the tests in December 2012.

• 

  open in a new window and use the zoom function of your browser

  otherwise download from here - Madiera's blood tests

  
  

and here is Madiera all grown up in Jan 2013 - a sleek young lady

UPDATE MAY 2015 - Madiera is still a happy healthy cat!

The Christmas Tomten

“Winters come and winters go, Summers come and summers go, Soon the swallows will be here.” thinks the Tomten.

Yuletide "the midpoint of winter - the cosmic balance between life and death". I feel like we are poised on such a tipping point - and i cant help thinking being in the southern hemisphere the december solstice signals the descent.

Mishka has been going 4 months on the FIP roller coaster. She's on Feline interferon twice a week and a weekly abdo drainage and one week into a trial of PI to see if we can tip the balance over toward life.

There are a few other kittens diagnosed around the same time still alive and well including Tomten - who is named after a scandinavian gnome who talks to the cat in tomten language, "a silent little language a cat can understand."

Nov 2012 "Our biggest fear in the storm was how to keep the feline interferon cold when we lost power. (My vet is importing it from the UK). Jan 1 will be the six month mark so we are thinking about doing another ultrasound then to see how everything looks. Knock on wood Gizmo also seems ok. Not sure how Gizmo would ever handle it if we loose Tom as they are inseparable." ~ Cassie

Gizmo and Tomten, the darker kitty who has FIP, live with the Hallbergs in New Jersey USA. He was diagnosed back in July 2012. His mom Cassie posts updates to the FIPcat support yahoo group. In october his dosages were prednisone 2mg daily and Feline Interferon injections .4ml weekly. Now it is down to every 2nd day for the prednisone and every ten days for the interferon.

Good Yule Tomten and family! Here is a video interpretation of the children's book 'The Tomten' to enjoy http://www.youtube.com/watch?v=ABMDcIJp784

Wednesday, December 12, 2012

Hi everyone- sorry its been a while since I posted. Hurricane Sandy did a number on our internet.

Tomten continues to do well. He will be at the 6 month mark since his initial diagnosis on Jan 1st 2012 (Big Day!!!) So for everyone who is new to this site and feeling at a total loss (That was me 6 months ago) there is hope!

For the most part he continues to do well. He is now on the feline interferon injections once every 10 days plus Prednisone every other day. The last two weeks he was a bit withdrawn and less active but the last two days he seems back to himself. (we live in total dread when his behavior changes the least little bit)

I took him and his brother Gizmo for their annual check up last Saturday. His regular vet (he also sees an internal medicine specialist who is leading the FIP treatment) was amazed by him. We decided to never vaccinate him again so as not to stress his immune system. She also took some blood to run a blood pannel. Both Vets agree that they want to rescan him again in January to see if the intestinal mass is still gone and if the lymph nodes are still inflamed.

I think his blood pannel looks much better: The Alb/Glob ration has gone from .44 back in July to .9. Which I think means no longer consistent with FIP. They key change is the alb which in July was 2.2 and now is 4.4. The glob hasn't changed much, its gone from 5.0 to 4.9.

There are some parameters that are really high but Dr. Harrison (the internal medicine vet was pleased. Marlene I would love to get your thoughts on it....

Bets wishes to everyone,

Cassie

Tomtens blood panel

CHEM 21 with COMPREHENSIVE CBC : CHEM 21 (1272)
Test Result Reference Range Low Normal High

ALK. PHOSPHATASE 6 0 - 62 U/L

ALT (SGPT) 35 28 - 100 U/L

AST (SGOT) 30 5 - 55 U/L

ALBUMIN 4.4 2.3 - 3.9 g/dL HIGH

TOTAL PROTEIN 9.3 5.9 - 8.5 g/dL HIGH

GLOBULIN 4.9 3.0 - 5.6 g/dL

TOTAL BILIRUBIN 0.0 0.0 - 0.4 mg/dL

DIRECT BILIRUBIN 0.0 0.0 - 0.2 mg/dL

BUN 37 15 - 34 mg/dL HIGH

CREATININE 1.2 0.8 - 2.3 mg/dL

CHOLESTEROL 142 82 - 218 mg/dL

GLUCOSE 114 70 - 150 mg/dL

CALCIUM 11.8 1
8.2 - 11.8 mg/dL

PHOSPHORUS 4.2 3.0 - 7.0 mg/dL

CHLORIDE 118 111 - 125 mEq/L

POTASSIUM 3.7 3.9 - 5.3 mEq/L LOW

SODIUM 157 147 - 156 mEq/L HIGH

A/G RATIO 0.9 0.4 - 0.8 HIGH

B/C RATIO 30.8 HIGH
INDIRECT BILIRUBIN 0.0 0 - 0.3 mg/dL

NA/K RATIO 42
HEMOLYSIS INDEX N 2

LIPEMIA INDEX N 3

Comments:
1. RESULT VERIFIED BY REPEAT ANALYSIS
2. Index of N,+,++ exhibits no significant effect on chemistry values.
3. Index of N,+,++ exhibits no significant effect on chemistry values.

CHEM 21 with COMPREHENSIVE CBC : CBC COMPREHENSIVE (1272)
Test Result Reference Range Low Normal High

WBC 6.3 4.2 - 15.6 K/uL

RBC 8.07 6.0 - 10.0 M/uL

HGB 12.8 9.5 - 15 g/dL

HCT 39.7 29 - 45 %

MCV 49 41 - 58 fL

MCH 15.9 11.0 - 17.5 pg

MCHC 32.2 29 - 36 g/dL

% RETICULOCYTE 0.1 %
RETICULOCYTE 8 3 - 50 K/uL

NEUTROPHILSEG 58.8 35 - 75 %

LYMPHOCYTES 30.5 20 - 55 %

MONOCYTES 5.0 1 - 4 % HIGH

EOSINOPHIL 5.4 2 - 12 %

BASOPHIL 0.3 0 - 1 %

AUTO PLATELET 192 170 - 600 K/uL

ANISOCYTOSIS SLIGHT
REMARKS SLIDE REVIEWED MICROSCOPICALLY.

ABSOLUTE NEUTROPHILSEG 3704 2500 - 12500 /uL

ABSOLUTE LYMPHOCYTE 1922 1500 - 7000 /uL

ABSOLUTE MONOCYTE 315 0 - 850 /uL

ABSOLUTE EOSINOPHIL 340 0 - 1500 /uL

ABSOLUTE BASOPHIL 19 0 - 100 /uL
_______________________________

14 December  2012

I love CR!!!! Cure is better but I love Clinical Response.

His total protein has gone up from 7.2 in July to 9.3. His Calcium has also gone up from 7.7 to 11.8.

He is eating well. Tomten has always lived to eat. I notice he sometimes now eats smaller amounts and then goes back and finishes it off 15 minutes later. In July his weight fell to 8.0 lbs he is up to 9.6 lbs.

Unfortunately he is addicted to fancy feast cat food which I fear may not be the most healthy but per Dr. Addie's recco I am supplementing it with a teaspoon a day of either Applepaws chicken, Tuna, Salmon. And he is getting raw steak 3 times a week. (Which he loves!!!) Makes up for the injections which he is increasingly getting more agitated about.

I will keep you posted on the scan in January.

For everyone who is new to the site and feeling hopeless (that was me in July- after all this was his second diagnosis of FIP- the first being a misdiagnosis when he was a kitten and actually had herpes. And I figured he couldn't get lucky twice and this was it). Hang in there! There is hope. Every day I have with Tom is a gift. I don't know how many we will have but we all treasure each day we have with our goofy fur ball and his brother.

Thanks to everyone for your continued support!

Cassie
__________________________________

22 September 2012

Subject: [FIPCatSupport] Update on Tomten- still doing well

Hi Everyone,  Its been a while since I posted. I contacted Dr. Addie and she agreed to consult with Dr. Harrison to see if Tomten really has or had fip and if he does to give us some advice on how to manage him since he is doing so well on the feline interferon. Now I am just waiting for the two to connect. Knock on wood he continues to do well. Went for a walk on his leash today outside and he was in kitty bliss!We are so grateful to still have him with us.

Dr.Addie was extremely helpful she suggested we immedietly take him off the L-lysine paste he has been taking for herpes since he was a kitten. Apparently, it interferes with the L'argine uptake. She also recommended we add raw red meat to his diet which Dr. Harrison is open to. So he is now getting chopped steak everyday and canned salmon from COSTCO. The steak is expensive but compared to the feline interferon a relative bargain! I also just ordered some applaws from amazon.com. Hopefully they will like it. His brother is super finkly and they really love their fancy feast but I am increasingly concerned I am feeding them yummy junk food. So we will see how it goes with the applaws.

Tomten is doing great but he is losing patience with us jabbing him every week. Upsetting for me as my once "velcro cat" is now nervous every time I pick him up that he is going to get jabbed. So hard because we can't explain it may be whats keeping him alive. But that being said the weather today was amazing and he loved going out for a walk with his brother.

One super goofy FIP moment is the family has taken to singing to Tomten and his brother Gizmo every night the "Kill the virus song" Modeled after Elmer Fudd's of bugs bunny fame "kill the wabbit song". I don't know that its helping but makes us all laugh and that seems to make the cats happy.

best thoughts to everyone, Cassie

14 January 2013 - click here for Tomtens update Great News!

John Robbie

"My beautiful John Robie. Still doing well 8 months after his FIP diagnosis. He is a miracle thanks to PI. ( Polyprenyl Immunostimulant ) " ~ CatMom: Lisa Cone

7th Dec 2012

John Robie on the stove - a favorite place. 33 weeks on PI and still going strong!

Happy Catmas John Robie and Lisa!

The charming Jon Robbie is named after the antihero of "To Catch a Thief" since he stole Lisa's heart!

• John Robie (approximate BD of June 25, 2010). 

  "John Robie is an active 2 year old, curious, kittenish loving brat. His Dry FIP is concentrated in his intestines and it can be uncomfortable for him to poop (he meows in the cat box), but he's otherwise a normal cat and has even gained some weight. He actually looks (and acts) like a normal (but not fat) teenage cat. It is difficult to remember that he has a fatal disease. But, he's a feisty one and strong. He bounced back from exploratory surgery like it didn't even phase him. I think I knew then that he was going to be my fighter and he sure has.

  He was dumped in a parking lot at 5 weeks old and found by me. He's probably some exotic mix as he is VERY different from all of other street cats. He had terrible fleas and ear mites when I found him and a slight URI but was otherwise healthy. He was just going to be a foster, but he was too amazing and I fell in love, so he became a part of a household with 8 other cats. When he was a year old, I fostered 3, 4 week old kittens for a few months. He was always and indoor cat. He started losing weight in late March and we took him in to our vet almost immediately. My normal vet diagnosed FIP immediately and told me he had a few weeks tops. I have too much experience with vets not being proactive so I went exploring. A client of mine (I'm a pet sitter) had a recent great experience with a vet that works with pug rescue (I also have pugs) so I took him there for a second opinion. They were much more proactive, did exploratory surgery, took a biopsy and was willing to work with getting him PI. 

  That vet was Airport Irvine Animal Hospital Irvine, CA. They also started him on Prednisone, Trental (pentoxifylline) and an appetite stimulant right away. He responded pretty well right away to the meds. We got approved for PI and he started on that on April 7. I weaned him slowly off of Pred, but when we got to the point where he had stopped the pred completely, he started doing badly again. I upped the pred to normal dosage again until he stabilized again, then weaned him down to .25 mg every other day. He has remained on .25 pred every other day, 1/8 Trental every other day and PI every other day since then and it has been the perfect combination thus far. 

  Oh, one other thing...None of the 8 other cats in my household (who are older than JR) have shown any signs of FIP (yet), nor have the foster kittens that were "raised" by JR shown any signs of FIP. I hope it stays that way. " ~ Lisa

  
  

  Amen to that.
  

  April 2013 update:

  
  

  

  still doing amazing!
  John Robie is still on Prednisone at one year. A dose of .25 ever other day seems to be the ticket for him. He does NOT do well when he is off completely.
  

  May 2013 update:

  His update is currently in flux. He was stable on the same dosage of all 3 meds. We decreased his Pred and he took a turn for the worst.

  We upped it back up to the original dosage then slowly decreased it weekly. As of 2 days ago, he is started showing symptoms again with the Pred at .25 every other day.

  So now we have increased it again to .25 every day.

  Hopefully that will stabilize him.

  The trental and PI dosage remains the same.
   
  Fortunately John Robbie is back to his playful self on the daily prednisone. Please be cautious when the cat is doing well; they really do look normal and start perhaps fussing about medications so that people try to scale the medications back. I have collected several case histories of cats who have had problems when their doses were scaled back like Abbey. Oliver Mackinnon takes his 5mls of PI DAILY for 3 years and only now is starting to think about scaling back, Blade has been chugging along on his meds for 2 years - if it ain't broke dont fix!